GeneTex中国官方网站
  • China

VE-Cadherin抗体 [GT1369]

Anti-VE-Cadherin antibody [GT1369] used in Western Blot (WB). GTX633705
Anti-VE-Cadherin antibody [GT1369] used in IHC (Paraffin sections) (IHC-P). GTX633705
Anti-VE-Cadherin antibody [GT1369] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX633705

目录号 GTX633705

文献引用 5

宿主

 Mouse

克隆

 Monoclonal

克隆编号

 GT1369

同种型

 IgG1

实验应用

 WB, ICC/IF, IHC-P

种属反应

 Human, Mouse
产品包装
100 μl (¥4000),
25 μl (¥1700)
查看所有 VE-Cadherin 的产品

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P Assay dependent
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

88 kDa. ( Note )

产品说明

This antibody was raised against human VE-cadherin Extracellular domain.

预测种属反应

Rat, Bovine, Pig(>80% identity)

产品属性

形式

Liquid

存储溶液

PBS, 20% Glycerol

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

1 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Synthetic peptide encompassing a sequence within the Extracellular domain of human VE-cadherin. The exact sequence is proprietary.

纯化方式

Affinity purified by Protein G.

偶联

Unconjugated

RRID

AB_2888370

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

cadherin 5 , 7B4 , CD144

细胞定位

Cell junction , Cell membrane; Single-pass type I membrane protein , Cell junction , Cell membrane

功能与背景

This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq]

数据库

研究领域

產品图片

Anti-VE-Cadherin antibody [GT1369] used in Western Blot (WB). GTX633705

GTX633705 WB Image

Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with VE-Cadherin antibody [GT1369] (GTX633705) diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Anti-VE-Cadherin antibody [GT1369] used in IHC (Paraffin sections) (IHC-P). GTX633705

GTX633705 IHC-P Image

VE-Cadherin antibody [GT1369] detects VE-Cadherin protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded human cervical carcinoma.
VE-Cadherin stained by VE-Cadherin antibody [GT1369] (GTX633705) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-VE-Cadherin antibody [GT1369] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX633705

GTX633705 ICC/IF Image

VE-cadherin antibody [GT1369] detects VE-cadherin protein at cell membrane by immunofluorescent analysis.
Sample: HUVEC cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: VE-cadherin protein stained by VE-cadherin antibody [GT1369] (GTX633705) diluted at 1:500.
Blue: Hoechst 33342 staining.
Scale bar = 10 μm.

文献引用

Application Reference

Liu IF et al. Biol Direct 2023; 18 (1) : 9 Long-term administration of Western diet induced metabolic syndrome in mice and causes cardiac microvascular dysfunction, cardiomyocyte mitochondrial damage, and cardiac remodeling involving caveolae and caveolin-1 expression.
实验应用 : IHC-P
种属反应 : Mouse
Martinez-Sanchez J et al. Bone Marrow Transplant 2020; The induction strategies administered in the treatment of multiple myeloma exhibit a deleterious effect on the endothelium.
实验应用 : ICC/IF
种属反应 : Human
Sheen YS et al. J Pathol 2020; 250 (4) : 452-463 Purpuric drug eruptions induced by EGFR tyrosine kinase inhibitors are associated with IQGAP1-mediated increase in vascular permeability.
实验应用 : ICC/IF
种属反应 : Human
Kachamakova-Trojanowska N et al. Cells 2019; 8 (11) Human iPSCs-Derived Endothelial Cells with Mutation in HNF1A as a Model of Maturity-Onset Diabetes of the Young.
实验应用 : ICC/IF
种属反应 : Human
Kudo H et al. Int Endod J 2018; (Epub) A potential role for the silent information regulator 2 homologue 1 (SIRT1) in periapical periodontitis.
实验应用 : ICC/IF
种属反应 : Human
我要回报文献

产品评论

目前没有使用 VE-Cadherin antibody [GT1369] (GTX633705) 的产品评论被收录。快发表第一篇产品评论吧！
我要评论产品
SDS
PBS.pdf
产品包装 报价 (¥)
¥ 4000
¥ 1700
联系经销商
欣博盛生物科技有限公司
欣博盛生物科技有限公司
(全国热线) 4006-800-892 / (深圳) 0755-26755892 / (北京) 010-88594029 / (上海) 021-34613729 / (广州) 18024516375 / (香港) +852-69410778
http://www.neobioscience.com
genetex@neobioscience.com