应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500-1:3000 |
| Assay dependent |
| Assay dependent |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
阳性对照
LNCap
预测种属反应
Mouse, Rat, Bovine, Pig(>80% identity)
形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant protein encompassing a sequence within the Extracellular domain of human TMPRSS2. The exact sequence is proprietary.
纯化方式
Purified by antigen-affinity chromatography.
偶联
Unconjugated
RRID
AB_1952298
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
transmembrane serine protease 2 , PP9284 , PRSS10
细胞定位
Cell membrane; Single-pass type II membrane protein , Transmembrane protease , serine 2 catalytic chain: Secreted
功能与背景
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
数据库
研究领域
![Anti-TMPRSS2 antibody [N2C3] used in IHC (Paraffin sections) (IHC-P). GTX100743](/upload/website/prouct_img/small/GTX100743/GTX100743_43579_20200417_IHC-P_1_w_23060100_485.webp "Anti-TMPRSS2 antibody [N2C3] used in IHC (Paraffin sections) (IHC-P). GTX100743")
![Anti-TMPRSS2 antibody [N2C3] used in IHC (Paraffin sections) (IHC-P). GTX100743](/upload/website/prouct_img/small/GTX100743/GTX100743_43579_20200417_IHC-P_w_23060100_346.webp "Anti-TMPRSS2 antibody [N2C3] used in IHC (Paraffin sections) (IHC-P). GTX100743")
![Anti-TMPRSS2 antibody [N2C3] used in Western Blot (WB). GTX100743](/upload/website/prouct_img/small/GTX100743/GTX100743_43579_20240329_WB_TPM_watermark_24040123_594.webp "Anti-TMPRSS2 antibody [N2C3] used in Western Blot (WB). GTX100743")
![Anti-TMPRSS2 antibody [N2C3] used in Western Blot (WB). GTX100743](/upload/website/prouct_img/small/GTX100743/GTX100743_20240411_citeab_WB_314_24041501_187.webp "Anti-TMPRSS2 antibody [N2C3] used in Western Blot (WB). GTX100743")
![Anti-TMPRSS2 antibody [N2C3] used in IHC (Paraffin sections) (IHC-P). GTX100743](/upload/website/prouct_img/normal/GTX100743/GTX100743_43579_20200417_IHC-P_1_w_23060100_485.webp "Anti-TMPRSS2 antibody [N2C3] used in IHC (Paraffin sections) (IHC-P). GTX100743")
![Anti-TMPRSS2 antibody [N2C3] used in IHC (Paraffin sections) (IHC-P). GTX100743](/upload/website/prouct_img/normal/GTX100743/GTX100743_43579_20200417_IHC-P_w_23060100_346.webp "Anti-TMPRSS2 antibody [N2C3] used in IHC (Paraffin sections) (IHC-P). GTX100743")
![Anti-TMPRSS2 antibody [N2C3] used in Western Blot (WB). GTX100743](/upload/website/prouct_img/normal/GTX100743/GTX100743_43579_20240329_WB_TPM_watermark_24040123_594.webp "Anti-TMPRSS2 antibody [N2C3] used in Western Blot (WB). GTX100743")
![Anti-TMPRSS2 antibody [N2C3] used in Western Blot (WB). GTX100743](/upload/website/prouct_img/normal/GTX100743/GTX100743_20240411_citeab_WB_314_24041501_187.webp "Anti-TMPRSS2 antibody [N2C3] used in Western Blot (WB). GTX100743")
