产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500 - 1:1000 |
| Assay dependent |
| 1:1000 - 1:2000 |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品说明
This antibody recognizes human Tie2 in western blot without cross reactivity with human Tie1.
产品属性
形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
200 μg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
hTie2 extracellular domain
纯化方式
Protein G purified
From tissue culture supernatant
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
CD202B , TEK , TEK receptor tyrosine kinase , TIE2 , VMCM , VMCM1
细胞定位
Cell membrane,Cell junction,Focal adhesion,Cytoplasm,Cytoskeleton,Secreted
功能与背景
This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
数据库
研究领域
產品图片
![Anti-TIE2 antibody [21G7] used in IHC (Paraffin sections) (IHC-P). GTX52471](/templates/default/js/lightbox/images/loading.gif "Anti-TIE2 antibody [21G7] used in IHC (Paraffin sections) (IHC-P). GTX52471")
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GTX52471 IHC-P Image
IHC-P analysis of formalin fixed human placenta tissue using GTX52471 TIE2 antibody [21G7].
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文献引用
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产品评论
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![Anti-TIE2 antibody [21G7] used in IHC (Paraffin sections) (IHC-P). GTX52471](/upload/website/prouct_img/small/GTX52471/GTX52471_20191119_IHC-P_w_23060900_106.webp "Anti-TIE2 antibody [21G7] used in IHC (Paraffin sections) (IHC-P). GTX52471")
![Anti-TIE2 antibody [21G7] used in IHC (Paraffin sections) (IHC-P). GTX52471](/upload/website/prouct_img/normal/GTX52471/GTX52471_20191119_IHC-P_w_23060900_106.webp "Anti-TIE2 antibody [21G7] used in IHC (Paraffin sections) (IHC-P). GTX52471")
