产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500 - 1:1000 |
| Assay dependent |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品说明
This antibody recognizes human Tie1 in western blot without cross reactivity with human Tie2.
产品属性
形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
200 μg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
hTie1 extracellular domain
纯化方式
Protein G purified
From tissue culture supernatant
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
JTK14 , TIE , TIE1 , tyrosine kinase with immunoglobulin like and EGF like domains 1
细胞定位
Cell membrane
功能与背景
This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
数据库
研究领域
產品图片
![Anti-TIE1 antibody [12D9] used in IHC (Paraffin sections) (IHC-P). GTX52470](/templates/default/js/lightbox/images/loading.gif "Anti-TIE1 antibody [12D9] used in IHC (Paraffin sections) (IHC-P). GTX52470")
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GTX52470 IHC-P Image
IHC-P analysis of formalin fixed human placenta tissue using GTX52470 TIE1 antibody [12D9].
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文献引用
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产品评论
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![Anti-TIE1 antibody [12D9] used in IHC (Paraffin sections) (IHC-P). GTX52470](/upload/website/prouct_img/small/GTX52470/GTX52470_20191119_IHC-P_w_23060900_496.webp "Anti-TIE1 antibody [12D9] used in IHC (Paraffin sections) (IHC-P). GTX52470")
![Anti-TIE1 antibody [12D9] used in IHC (Paraffin sections) (IHC-P). GTX52470](/upload/website/prouct_img/normal/GTX52470/GTX52470_20191119_IHC-P_w_23060900_496.webp "Anti-TIE1 antibody [12D9] used in IHC (Paraffin sections) (IHC-P). GTX52470")
