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SARS-CoV / SARS-CoV-2 (COVID-19) spike抗体 [1A9]

Comparison Orthogonal
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunoprecipitation (IP). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Flow cytometry (FACS). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC-P (cell pellet) (IHC-P (cell pellet)). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC (Paraffin sections) (IHC-P). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC (Paraffin sections) (IHC-P). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC-P (cell pellet) (IHC-P (cell pellet)). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC (Paraffin sections) (IHC-P). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604

目录号 GTX632604

文献引用 380
10

宿主

 Mouse

克隆

 Monoclonal

克隆编号

 1A9

同种型

 IgG1

实验应用

 WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP, ELISA, EM, Neutralizing/Inhibition, Sandwich ELISA, IHC-P (cell pellet)

种属反应

 SARS Coronavirus, SARS Coronavirus 2
产品包装
100 μl (¥4000),
25 μl (¥1700)
查看所有 SARS-CoV-2 (COVID-19) Spike 的产品

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB 1:500-1:3000
ICC/IF 1:100-1:2000
IHC-P 1:100-1:500
IHC-Fr Assay dependent
FACS Assay dependent
IP Assay dependent
ELISA Assay dependent
EM Assay dependent
Neutralizing/Inhibition Assay dependent
Sandwich ELISA Assay dependent
IHC-P (cell pellet) Assay dependent

Note :

IHC-P
Recommended heat-Induced Epitope Retrieval pH 6.0 for 20 minutes.

Sandwich ELISA
Capture : GTX632604, Detection: GTX635654 / GTX135356 / GTX635672 / GTX135386 / GTX135360 / GTX635910 / GTX635911 / GTX635693 / GTX635792 / GTX635793 / GTX635713.
Recommend using GTX400033 (Trident RIPA Lysis Buffer with low SDS) as dilution buffer for diluting samples and antibodies in sandwich ELISA assay if including GTX632604 as capture antibody.
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

产品说明

This antibody detects both SARS-CoV spike and SARS-CoV-2 spike proteins (S2 subunit). Based on sequence analysis, this antibody is predicted to recognize S2' subunit. Our internal testing indicates no cross-reactivity with MERS-CoV spike protein.This antibody is able to detect multiple SARS-CoV-2 VOCs, including Omicron variant.

产品属性

形式

Liquid

存储溶液

PBS

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

1 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

SARS Coronavirus

免疫原

The immunogen used to generate this antibody corresponds to SARS-CoV SΔ10 (within S2 domain) protein (1029-1192 a.a.). (SARS-CoV strain: Sin2774) The exact sequence is proprietary.

纯化方式

Affinity purified by Protein G.

偶联

Unconjugated

RRID

AB_2864418

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

2019-nCoV Spike , SARS-CoV-2 Spike , COVID-19 Spike

研究领域

產品图片

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604

GTX632604 ICC/IF Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV-2 (COVID-19) spike protein by immunofluorescent analysis.
Sample: BHK-21 cells transfected with full-length SARS-CoV-2 spike were fixed in 4% paraformaldehyde at RT for 30 min.
Green: SARS-CoV-2 (COVID-19) spike stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:2000.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant full-length SARS-CoV-2 spike (trimer) protein using GTX632604 as capture antibody at concentration of 5 μg/mL and GTX635672 as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Indirect ELISA analysis was performed by coating the plate with recombinant SARS-CoV-2 (COVID-19) Spike (ECD) Protein, Omicron / BA.2.12.1 variant, His tag (GTX137114-pro) (28.62-0.45 nM). Coated protein was probed with the specified SARS-CoV-2 (COVID-19) Spike antibodies (1 μg/mL). Goat anti-rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) or goat anti-mouse IgG antibody (HRP) (GTX213111-01) (1:10000) were used to detect the bound primary antibodies.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Indirect ELISA analysis was performed by coating the plate with recombinant SARS-CoV-2 spike (ECD) trimer, omicron BA.2.75 variant, His tag (GTX137533-pro) (28.62-0.45 nM). Coated protein was probed with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (the specified SARS-CoV-2 (COVID-19) Spike antibodies) (1 μg/mL). Goat anti-mouse IgG antibody (HRP) (GTX213111-01) (1:10000) was used to detect the bound primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunoprecipitation (IP). GTX632604

GTX632604 IP Image

Immunoprecipitation of SARS-CoV-2 Spike transfected 293T whole cell extracts using 2 μg of SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604).
Western blot analysis was performed using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604).
EasyBlot HRP-conjugated anti mouse IgG antibody (GTX221667-01) was used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of non-transfected (GTX535673) and SARS-CoV-2 spike (full length) transfected (GTX535664) 293T whole cell extracts using GTX632604 as capture antibody at concentration of 5 μg/mL and GTX135356 as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Comparison

Indirect ELISA analysis was performed by coating the plate with recombinant SARS-CoV-2 (COVID-19) Spike (ECD) Protein, BA.2 / Omicron variant, His tag (GTX137037-pro) (29.71-0.46 nM). Coated protein was probed with the specified SARS-CoV-2 (COVID-19) Spike antibodies (1 μg/mL). Goat anti-rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) or goat anti-mouse IgG antibody (HRP) (GTX213111-01) (1:10000) were used to detect the bound primary antibodies.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604

GTX632604 WB Image

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604

GTX632604 WB Image

Non-infected (–) and infected (+, 48h pl MOI 0.01) Caco-2 whole cell extracts were separated by SDS-PAGE, and the membrane was blotted with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:1000.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Indirect ELISA analysis was performed by coating plate with 50 μL of recombinant SARS-CoV-2 (COVID-19) spike S2 ECD protein at concentrations ranging from 0.0625 μg/mL to 4 μg/mL. The coated protein is detected with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) at 1 μg/mL. Mouse IgG antibody (HRP) (GTX213111-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 (COVID-19) Spike (ECD) protein, His tag (active) (GTX135972-pro) using antibodies as below.

Capture: SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (5 μg/mL)
Detection: SARS-CoV-2 (COVID-19) Spike S2 antibody [HL1038] (GTX635910) (1 μg/mL)

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Flow cytometry (FACS). GTX632604

GTX632604 FACS Image

FACS analysis of 293T cells infected with recombinant vaccinia virus carrying the Spike gene using GTX632604 SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9].

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 (COVID-19) Spike S2 (ECD) protein, mouse IgG Fc tag protein (GTX135684-pro) using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) as capture antibody at concentration of 5 μg/mL and SARS-CoV-2 (COVID-19) Spike S2 antibody [HL237] (GTX635693) as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC-P (cell pellet) (IHC-P (cell pellet)). GTX632604

GTX632604 IHC-P (cell pellet) Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV-2 (COVID-19) spike protein by immunohistochemical analysis.
Sample: Mock (GTX435670) and SARS-CoV-2 (COVID-19) Spike transfected 293T cell FFPE Cell Pellet Block (GTX435640).
Red: SARS-CoV-2 (COVID-19) spike stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:1000.
Blue: Fluoroshield with DAPI (GTX30920).
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant Spike ECD protein(s) derived from different strains of SARS-CoV-2 virus (ie., Wild type; B.1.1.7 alpha variant; B.1.351 beta variant; P.1 gamma variant; B1.617.2 delta variant) using antibodies as below.

Capture: SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (5 μg/mL)
Detection: SARS-CoV-2 (COVID-19) Spike S1 antibody [HL13402] (GTX635713) (1 μg/mL)

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of non-transfected (GTX535673) and SARS-CoV-2 spike (full length) transfected (GTX535664) 293T whole cell extracts using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) as capture antibody at concentration of 5 μg/mL and SARS-CoV-2 (COVID-19) Spike S1 antibody [HL6] (GTX635654) as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC (Paraffin sections) (IHC-P). GTX632604

GTX632604 IHC-P Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) detects SARS-CoV-2 (COVID-19) spike protein by immunohistochemical analysis of SARS-CoV-2 infected human placenta (left) and normal human placenta (right).

The IHC-P was performed by HISTOWIZ.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604

GTX632604 ICC/IF Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] protein by immunofluorescent analysis.
Sample: Mock and transfected 293T cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green:SARS-CoV-2 (COVID-19) spike protein stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:1000.
Blue: Fluoroshield with DAPI (GTX30920).

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Indirect ELISA analysis performed by coating plate with recombinant SARS-CoV-2 (COVID-19) Spike (L18F,..., K417T, E484K, N501Y, D614G,...,V987P)(ECD), His tag (active) (B.1.1.28) (GTX136091-pro) and SARS-CoV-2 (COVID-19) Spike (ECD) protein, His tag (active) (WT) (GTX135972-pro) (4000-62.5 ng/mL). Coated protein was probed with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (1 μg/mL). Mouse IgG antibody (HRP) (GTX213111-01) (1:10000) was used to detect bound primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of non-transfected and transfected 293T whole cell extracts using GTX632604 as capture antibody at concentration of 5 μg/mL and GTX135360 as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604

GTX632604 WB Image

SARS-CoV-2 (COVID-19) Spike (del69-70,del144,N501Y,A570D,D614G,...,D1118H) (ECD) Protein, His tag (GTX136059-pro, 0.25 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 spike (trimer) protein using antibodies as below.
Capture: SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (5 μg/mL)
Detection: SARS-CoV-2 (COVID-19) Spike S2 antibody [HL1038] (GTX635910) (1 μg/mL).

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 (COVID-19) Spike S2 (ECD) protein, human IgG Fc tag (GTX01559-pro) using antibodies as below.
Capture: SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (5 μg/mL)
Detection: Human IgG antibody (HRP) (1:200000 )

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC (Paraffin sections) (IHC-P). GTX632604

GTX632604 IHC-P Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) detects SARS-CoV-2 (COVID-19) spike protein by immunohistochemical analysis of SARS-CoV-2 infected human lung.

The IHC-P was performed by HISTOWIZ.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant Spike ECD protein(s) derived from different strains of SARS-CoV-2 virus (ie., Wild type; B.1.1.7 alpha variant; B.1.351 beta variant; P.1 gamma variant; B1.617.2 delta variant) using antibodies as below.

Capture: SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (5 μg/mL)
Detection: SARS-CoV-2 (COVID-19) Spike RBD antibody [HL1003] (GTX635792) (1 μg/mL)

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 (COVID-19) Spike S2 (ECD) protein, human IgG Fc tag (GTX01559-pro) using antibodies as below.
Capture: SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (5 μg/mL)
Detection: Goat Anti-Human IgG antibody (HRP) (1:200000)

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604

GTX632604 WB Image

SARS-CoV-2 (COVID-19) Spike ( L18F,..., K417N, E484K, N501Y,...)(ECD) Protein, His tag (active) (GTX136061-pro, 0.2 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 spike (trimer) protein using antibodies as below.
Capture: SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (5 μg/mL)
Detection: SARS-CoV-2 (COVID-19) Spike S1 antibody [HL263] (GTX635672) (1 μg/mL).

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 spike (trimer) protein using antibodies as below.
Capture: SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (5 μg/mL)
Detection: SARS-CoV-2 (COVID-19) Spike RBD antibody [HL1003] (GTX635792) (1 μg/mL).

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Indirect ELISA analysis was performed by coating the plate with recombinant SARS-CoV-2 (COVID-19) Spike (ECD) Protein, Omicron / BF.7 variant, His tag (GTX137880-pro) (28.78-0.45 nM). Coated protein was probed with the specified SARS-CoV-2 (COVID-19) Spike antibodies (1 μg/mL). Goat anti-rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) or goat anti-mouse IgG antibody (HRP) (GTX213111-01) (1:10000) was used to detect the bound primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Indirect ELISA analysis was performed by coating the plate with recombinant SARS-CoV-2 (COVID-19) Spike (ECD) Protein, Omicron / BQ.1 variant, His tag (GTX137881-pro) (28.78-0.45 nM). Coated protein was probed with the specified SARS-CoV-2 (COVID-19) Spike antibodies (1 μg/mL). Goat anti-rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) or goat anti-mouse IgG antibody (HRP) (GTX213111-01) (1:10000) was used to detect the bound primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604

GTX632604 ICC/IF Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV-2 by immunofluorescent analysis.
Sample: Vero E6 cells were infected with SARS-CoV-2 (MOI of 1) and fixed with chilled methanol/acetone.
Green: SARS-CoV-2 infected Vero E6 cells stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604).
Blue: Nuclei were counterstained with DAPI.

*From Zheng Z, et al. bioRxiv(2020). Shown under license agreement

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC-P (cell pellet) (IHC-P (cell pellet)). GTX632604

GTX632604 IHC-P (cell pellet) Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV / SARS-CoV-2 (COVID-19) spike protein by immunohistochemical analysis.
Sample: Paraffin-embedded SARS-CoV-2 (COVID-19) Spike FFPE Cell Pellet Block.
Red: SARS-CoV / SARS-CoV-2 (COVID-19) spike stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:1000.
Green: SARS-CoV-2 (COVID-19) spike stained by SARS-CoV-2 (COVID-19) spike antibody (GTX135356) diluted at 1:1000.
Blue: Fluoroshield with DAPI (GTX30920).
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 spike (trimer) protein using antibodies as below.
Capture: SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (5 μg/mL)
Detection: SARS-CoV-2 (COVID-19) Spike S1 antibody [HL13402] (GTX635713) (1 μg/mL).

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant full-length SARS-CoV-2 spike (trimer) protein using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) as capture antibody at concentration of 5 μg/mL and SARS-CoV-2 (COVID-19) Spike RBD antibody (GTX135709) as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 (COVID-19) Spike S2 (ECD) protein, human IgG Fc tag (GTX01559-pro) using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) as capture antibody at concentration of 5 μg/mL and Human IgG antibody (HRP) (1:200000) as detection antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC (Paraffin sections) (IHC-P). GTX632604

GTX632604 IHC-P Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV-2 (COVID-19) spike protein by immunohistochemical analysis of infected human placenta.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Indirect ELISA analysis performed by coating plate with recombinant Spike ECD protein(s) derived from different strains of SARS-CoV-2 virus (ie., Wild type; B1.617.2 delta variant) (29.71-0.46 nM). Coated protein was probed with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (1 μg/mL). Goat anti-mouse IgG antibody (HRP) (GTX213111-01) (1:10000) was used to detect bound primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant Spike ECD protein(s) derived from different strains of SARS-CoV-2 virus (ie., Wild type; B.1.1.7 alpha variant; B.1.351 beta variant; P.1 gamma variant; B1.617.2 delta variant) using antibodies as below.

Capture: SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (5 μg/mL)
Detection: SARS-CoV-2 (COVID-19) Spike S1 antibody [HL263] (GTX635672) (1 μg/mL)

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Indirect ELISA analysis performed by coating plate with recombinant SARS-CoV-2 (COVID-19) Spike ( L18F,..., K417N, E484K, N501Y,...)(ECD) Protein, His tag (active) (South Africa variant) (GTX136061-pro) and SARS-CoV-2 (COVID-19) Spike (ECD) protein, His tag (active) (GTX135972-pro) (4000-62.5 ng/mL). Coated protein was probed with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (1 μg/mL). Mouse IgG antibody (HRP) (GTX213110-01) (1:10000) was used to detect bound primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Indirect ELISA analysis was performed by coating the plate with recombinant SARS-CoV-2 (COVID-19) Spike (ECD) Protein, Omicron / BA.4 / BA.5 variant, His tag (GTX137113-pro) (28.78-0.45 nM). Coated protein was probed with the specified SARS-CoV-2 (COVID-19) Spike S1 antibodies (1 μg/mL). Goat anti-rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) or goat anti-mouse IgG antibody (HRP) (GTX213111-01) (1:10000) were used to detect the bound primary antibodies.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 (COVID-19) Spike S2 (T716I, S982A, D1118H Mutant) (ECD) protein, His tag (GTX136023-pro), SARS-CoV-2 (COVID-19) Spike S2 (ECD) protein, mouse IgG Fc tag (GTX135684-pro), and SARS-CoV-2 (COVID-19) Spike S2 (ECD) protein, human IgG Fc tag (GTX01559-pro) using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) as capture antibody at concentration of 5 μg/mL and SARS-CoV-2 (COVID-19) Spike S2 antibody [HL1038] (GTX635910) as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 (COVID-19) Spike S2 (T716I, S982A, D1118H Mutant) (ECD) protein, His tag (GTX136023-pro) and SARS-CoV-2 (COVID-19) Spike S2 (ECD) protein, human IgG Fc tag (GTX01559-pro) using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) as capture antibody at concentration of 5 μg/mL and SARS-CoV-2 (COVID-19) Spike S2 antibody [HL1039] (GTX635911) as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Indirect ELISA analysis performed by coating plate with recombinant SARS-CoV-2 (COVID-19) Spike (ECD) Protein, B.1.1.529 / Omicron variant, His tag (GTX136780-pro) (29.71-0.46 nM). Coated protein was probed with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (1 μg/mL). Goat anti-mouse IgG antibody (HRP) (GTX213111-01) (1:10000) was used to detect bound primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Indirect ELISA analysis performed by coating plate with recombinant full-length SARS-CoV-2 (501.V1) spike protein, SARS-CoV-2 (501.V2) spike protein and SARS-CoV-2 spike protein (4000-62.5 ng/mL). Coated protein was probed with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) (1 μg/mL). Mouse IgG antibody (HRP) (GTX213110-01) (1:10000) was used to detect bound primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 (COVID-19) Spike S2 (T716I, S982A, D1118H Mutant) (ECD) protein, His tag (GTX136023-pro) using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) as capture antibody at concentration of 5 μg/mL and SARS-CoV-2 (COVID-19) Spike S2 antibody [HL237] (GTX635693) as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604

GTX632604 WB Image

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604

GTX632604 WB Image

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604

GTX632604 WB Image

SARS-CoV-2 (COVID-19) Spike (ECD) Protein, B.1.1.529 / Omicron variant, His tag (1 μg, GTX136780-pro) were separated by 12% SDS-PAGE, and the membrane was blotted with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604

GTX632604 ICC/IF Image

The data was published in the 2022 in Int J Mol Sci. PMID: 35805887

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604

GTX632604 ICC/IF Image

The data was published in the 2022 in Int J Mol Sci. PMID: 35805887

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604

GTX632604 WB Image

The data was published in the 2020 in Sci Rep. PMID: 33318562

文献引用

Application Reference

L Du et al. Commun Biol 2024; 7 (1) : 486 A viral assembly inhibitor blocks SARS-CoV-2 replication in airway epithelial cells
实验应用 : WB
N Yoshida et al. Wellcome Open Research 2024; Human placental cells are resistant to SARS-CoV-2 infection and replication
实验应用 : ICC/IF
Inoue T et al. iScience 2024; 27 (4) : 109363 Overcoming antibody-resistant SARS-CoV-2 variants with bispecific antibodies constructed using non-neutralizing antibodies.
Lin CH et al. Int J Mol Sci 2024; 25 (5) Inhibitory Efficacy of Main Components of Scutellaria baicalensis on the Interaction between Spike Protein of SARS-CoV-2 and Human Angiotensin-Converting Enzyme II.
S Clever et al. Viruses 2024; 16 (3) : 417 Single MVA-SARS-2-ST/N Vaccination Rapidly Protects K18-hACE2 Mice against a Lethal SARS-CoV-2 Challenge Infection
实验应用 : WB
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SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] 目录号 GTX632604

Rating
( Average 5 based on 10 users reviews)
实验应用
Western Blot(WB)
( Average 5 based on 2 users reviews)
Immunocytochemistry/ Immunofluorescence(ICC/IF)
( Average 5 based on 3 users reviews)
IHC (Paraffin sections)(IHC-P)
( Average 5 based on 3 users reviews)
Flow cytometry(FACS)
( Average 5 based on 1 users reviews)
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC (Paraffin sections) (IHC-P). GTX632604
Date : Anonymous submitted on 07-Mar-2022
Score :
Application Tested : IHC-P
Sample : Huma skin tissue specimen
Blocking : 0.3% H2O2 meta, RT, 0.5Hr
Fixation : 10% formalin
Permeabilization /Antigen retrieval : Citrate buffer (ph 6.0)
Primary Antibody : 1:500, 4°C, > 12Hr
条带说明 : Eczema after vaccination. The patient was COVID-19 negative. The signals were accumulated spike proteins which have been produced after mRNA vaccination.
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC (Paraffin sections) (IHC-P). GTX632604
Date : Anonymous submitted on 02-Aug-2020
Score :
Application Tested : IHC-P
Sample Species : SARS-CoV-2
Sample : Human placenta tissue
Fixation : neutral buffered formalin, 25°C, 24Hr
Permeabilization /Antigen retrieval : Citrate buffer pH6, 97°C, 0.3Hr
Primary Antibody : 1:100, 25°C, 0.5Hr
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Flow cytometry (FACS). GTX632604
Date : Anonymous submitted on 14-Jul-2020
Score :
Application Tested : FACS
Sample Species : SARS-CoV-2
Sample : Vero E6 cells infected with SARS-CoV-2 USA-WA1/2020
Fixation : 4% formaldehyde in PBS
Permeabilization /Antigen retrieval : BD Cytofix/Cytoperm
Primary Antibody : 1:100, 25°C, 0.5Hr
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC (Paraffin sections) (IHC-P). GTX632604
Date : Anonymous submitted on 21-Jun-2020
Score :
Application Tested : IHC-P
Sample Species : SARS-CoV-2
Sample : Human lung tissue
Blocking : 2% BSA + 5% donkey serum + 0.15% PBST, 25°C, 1Hr
Permeabilization /Antigen retrieval : 1% Triton, Sodium Citrate Buffer
Primary Antibody : 1:500, 4°C, 16Hr
Figure Note : Green: SARS-CoV-2 (COVID-19) spike stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604).
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604
Date : Anonymous submitted on 21-Jun-2020
Score :
Application Tested : ICC/IF
Sample Species : SARS-CoV-2
Sample : SARS-CoV-2 FL spike transfected HeLa cells
Primary Antibody : 1μg/ml, 4°C, 16Hr
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604
Date : Mohamed Gadalla submitted on 19-Jun-2020
Score :
Application Tested : WB
Sample Species : SARS-CoV-2
Sample : 293T cells
Amount used : 25 μg
Blocking : 5% non-fat dry milk in PBST, 25°C, 1Hr
Primary Antibody : 1:1000, 4°C, 16Hr
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604
Date : Anonymous submitted on 17-Jun-2020
Score :
Application Tested : ICC/IF
Sample Species : SARS-CoV-2
Sample : SARS-CoV-2 spike transfected 293T cells
Fixation : 4% PFA, 25°C, 0.5Hr
Primary Antibody : 1:200, 1°C, 25Hr
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9]. GTX632604
Date : Anonymous submitted on 31-Mar-2020
Score :
Sample Species : SARS-CoV
Sample : SARS-CoV infected 293T cells
Amount used : 10 μg
Blocking : BSA, 1Hr
Primary Antibody : 1:1000, 25°C, 1Hr
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604
Date : Anonymous submitted on 10-Mar-2020
Score :
Application Tested : ICC/IF
Sample Species : SARS-CoV-2
Sample : BHK-21 transfected with full-length SARS-CoV-2 spike
Fixation : PFA, 0.5Hr
Primary Antibody : 1:2000, 4°C, 4Hr
Figure Note : Green: SARS-CoV-2 (COVID-19) spike stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604).
Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604
Date : Anonymous submitted on 01-Mar-2020
Score :
Application Tested : WB
Sample Species : SARS-CoV, SARS-CoV-2
Sample : SARS-CoV / SARS-CoV-2 infected Caco-2 cells
Amount used : 20 μg
Blocking : 5% milk in PBST, 20°C, 0.5Hr
Primary Antibody : 1:1000, 4°C, 16Hr
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Application Reference
L Du et al. Commun Biol 2024; 7 (1):486 A viral assembly inhibitor blocks SARS-CoV-2 replication in airway epithelial cells
实验应用 : WB
N Yoshida et al. Wellcome Open Research 2024; Human placental cells are resistant to SARS-CoV-2 infection and replication
实验应用 : ICC/IF
Inoue T et al. iScience 2024; 27 (4):109363 Overcoming antibody-resistant SARS-CoV-2 variants with bispecific antibodies constructed using non-neutralizing antibodies.
Lin CH et al. Int J Mol Sci 2024; 25 (5) Inhibitory Efficacy of Main Components of Scutellaria baicalensis on the Interaction between Spike Protein of SARS-CoV-2 and Human Angiotensin-Converting Enzyme II.
W-F Tang et al. Antimicrob Agents Chemother 2024;:e0095623 BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir
实验应用 : WB
S Zorad et al. Physiol Res 2024; 73:27-35 Angiotensin I and II Stimulate Cell Invasion of SARS-CoV-2: Potential Mechanism via Inhibition of ACE2 Arm of RAS
实验应用 : WB
S Clever et al. Viruses 2024; 16 (3):417 Single MVA-SARS-2-ST/N Vaccination Rapidly Protects K18-hACE2 Mice against a Lethal SARS-CoV-2 Challenge Infection
实验应用 : WB
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Zhang F et al. mBio 2024; 15 (2):e0167223 SARS-CoV-2 spike glycosylation affects function and neutralization sensitivity.
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Limanaqi F et al. Biol Res 2024; 57 (1):2 Alpha-synuclein dynamics bridge Type-I Interferon response and SARS-CoV-2 replication in peripheral cells.
T Iida et al. Research Square 2024; High-throughput Light-induced Immunoassay under One-minute Antibody-coating with Energy Saving Nanoparticle-imprinted Substrate
Zuo Y et al. EMBO Rep 2023; 24 (4):e56374 Vitamin C promotes ACE2 degradation and protects against SARS-CoV-2 infection.
Normandin E et al. J Neuropathol Exp Neurol 2023; 82 (4):283-295 Neuropathological features of SARS-CoV-2 delta and omicron variants.
Bhargava A et al. iScience 2023; 26 (12):108449 Transcriptomic analysis of sorted lung cells revealed a proviral activity of the NF-κB pathway toward SARS-CoV-2.
Fujita S et al. J Virol 2023; 97 (10):e0099023 Determination of the factors responsible for the tropism of SARS-CoV-2-related bat coronaviruses to Rhinolophus bat ACE2.
Kimura I et al. J Virol 2023; 97 (10):e0101123 Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics.
A Kachko et al. Vaccine 2023; S0264-410X (23):01498-6 Vaccine-associated respiratory pathology correlates with viral clearance and protective immunity after immunization with self-amplifying RNA expressing the spike (S) protein of SARS-CoV-2 in mouse models
实验应用 : WB
M Nogami et al. Research Square 2023; Anti-Spike Protein Antibody Immunoreactivity Is Widely Expressed in Human Lymph Nodes with or without Pfizer-BioNTech or Moderna mRNA Vaccination in Non-Infected Individuals
Carvalhal F et al. Molecules 2023; 28 (20) Evaluation of the Cytotoxic and Antiviral Effects of Small Molecules Selected by In Silico Studies as Inhibitors of SARS-CoV-2 Cell Entry.
L?cuyer D et al. Front Immunol 2023; 14:1270081 The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection.
Zhang P et al. Proc Natl Acad Sci U S A 2023; 120 (29):e2305896120 Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus-like particles.
Streblow DN et al. Nat Commun 2023; 14 (1):7062 Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology.
Cui Q et al. MedComm (2020) 2023; 4 (5):e400 The Apolipoprotein E neutralizing antibody inhibits SARS-CoV-2 infection by blocking cellular entry of lipoviral particles.
CF Yang et al. J Biomed Sci 2023; Human ACE2 protein is a molecular switch controlling the mode of SARS-CoV-2 transmission
Cottignies-Calamarte A et al. STAR Protoc 2023; 4 (4):102593 Protocol to detect infectious SARS-CoV-2 at low levels using in situ hybridization techniques.
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C Di Primio et al. PNAS Nexus 2023; 2 (9):pgad282 Severe acute respiratory syndrome coronavirus 2 infection leads to Tau pathological signature in neurons
实验应用 : WB
TR Ullah et al. Nat Commun 2023; 14 (1):5666 Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection
实验应用 : ICC/IF
N Ahmed et al. Viruses 2023; 15 (9):1921 microRNA-185 Inhibits SARS-CoV-2 Infection through the Modulation of the Host’s Lipid Microenvironment
实验应用 : WB
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T Deckert-Gaudig et al. ChemRxiv 2023; Identification of RNA-containing virus particles using a triple correlative morphological and microscopic approach
实验应用 : ICC/IF
F Hornung et al. Int J Obes (Lond) 2023; Thoracic adipose tissue contributes to severe virus infection of the lung
实验应用 : IHC-Fr
Sandra E. Reznik et al. Biomolecules 2023; 13 (8):1224 SARS-CoV-2 Infection in Unvaccinated High-Risk Pregnant Women in the Bronx, NY, USA Is Associated with Decreased Apgar Scores and Placental Villous Infarcts
M Azarias Da Silva et al. Sci Adv 2023; 9 (31):eadg2122 Repetitive mRNA vaccination is required to improve the quality of broad-spectrum anti–SARS-CoV-2 antibodies in the absence of CXCL13
实验应用 : FACS
Zhang F et al. bioRxiv 2023; SARS-CoV-2 spike glycosylation affects function and neutralization sensitivity.
Sayedahmed EE et al. Mol Ther Methods Clin Dev 2023; 30:194-207 Impact of an autophagy-inducing peptide on immunogenicity and protection efficacy of an adenovirus-vectored SARS-CoV-2 vaccine.
Yang J et al. Nat Microbiol 2023; 8 (1):121-134 Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2.
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Kuzmina A et al. Heliyon 2023; 9 (6):e16750 Changes within the P681 residue of spike dictate cell fusion and syncytia formation of Delta and Omicron variants of SARS-CoV-2 with no effects on neutralization or infectivity.
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2023; Changes within the P681 residue of spike dictate cell fusion and syncytia formation of Delta and Omicron variants of SARS-CoV-2 with no effects on neutralization or infectivity
实验应用 : WB
PS Sung et al. EMBO Mol Med 2023;:e16351 Inhibition of SARS-CoV-2-mediated thromboinflammation by CLEC2.Fc
实验应用 : ELISA
Alena Reguzova et al. Research Square 2023; A novel multi-antigenic parapoxvirus-based vaccine demonstrates efficacy in protecting hamsters and non-human primates against SARS-CoV-2 challenge
实验应用 : WB
SB Park et al. Commun Biol 2023; 6 (1):556 SARS-CoV-2 omicron variants harbor spike protein mutations responsible for their attenuated fusogenic phenotype
实验应用 : ICC/IF
Asiedu SO et al. Int J Mol Sci 2023; 24 (8) Mycolactone: A Broad Spectrum Multitarget Antiviral Active in the Picomolar Range for COVID-19 Prevention and Cure.
Satish Pillai et al. Research Square 2023; A Novel Viral Assembly Inhibitor Blocks SARS-CoV-2 Replication in Airway Epithelial Cells
实验应用 : WB
L Lebrun et al. Acta Neuropathol Commun 2023; SARS-Cov-2 infection and neuropathological findings: a report of 18 cases and review of the literature
实验应用 : IHC-P
Lorenzo, M.M. et al. Biology and Life Sciences, Virology 2023; Vaccinia Virus Strain Mva Expressing a Prefusion-Stabilized SARS-CoV-2 Spike Glycoprotein Induces Robust Protection and Prevents Brain Infection in Mouse and Hamster Models
实验应用 : WB
Swain LA et al. Hepatol Commun 2023; 7 (4) Acute severe hepatitis as a presenting symptom in clinically stable patients admitted with SARS-CoV-2 Omicron infection.
实验应用 : IHC-P
Mohammad TSH et al. Int J Mol Sci 2023; 24 (6) In Silico Binding of 2-Aminocyclobutanones to SARS-CoV-2 Nsp13 Helicase and Demonstration of Antiviral Activity.
实验应用 : ICC/IF
Metzler M et al. Mol Cell Proteomics 2023;:100537 SARS-CoV-2 variants show different host cell proteome profiles with delayed immune response activation in Omicron-infected cells.
实验应用 : ICC/IF
Horndler L et al. Front Immunol 2023; 14:1157263 Decreased breadth of the antibody response to the spike protein of SARS-CoV-2 after repeated vaccination.
实验应用 : ICC/IF
Bussani R et al. J Pathol 2023; 259 (3):254-263 Persistent SARS-CoV-2 infection in patients seemingly recovered from COVID-19.
实验应用 : IHC-P
Furusawa Y et al. EBioMedicine 2023; 91:104561 In SARS-CoV-2 delta variants, Spike-P681R and D950N promote membrane fusion, Spike-P681R enhances spike cleavage, but neither substitution affects pathogenicity in hamsters.
实验应用 : WB
Luo Y et al. Cell Discov 2023; 9 (1):40 High-throughput screening of spike variants uncovers the key residues that alter the affinity and antigenicity of SARS-CoV-2
实验应用 : WB
Piranej S et al. bioRxiv 2023; Rolosense: Mechanical detection of SARS-CoV-2 using a DNA-based motor.
Meseguer S et al. Front Microbiol 2023; 14:1066493 SARS-CoV-2-encoded small RNAs are able to repress the host expression of SERINC5 to facilitate viral replication.
实验应用 : WB
Brogna C et al. Int J Mol Sci 2023; 24 (4) Analysis of Bacteriophage Behavior of a Human RNA Virus, SARS-CoV-2, through the Integrated Approach of Immunofluorescence Microscopy, Proteomics and D-Amino Acid Quantification.
实验应用 : ICC/IF
Ham Y et al. Biosens Bioelectron 2023; 227:115169 The SpACE-CCM: A facile and versatile cell culture medium-based biosensor for detection of SARS-CoV-2 spike-ACE2 interaction.
实验应用 : Neutralizing/Inhibition
Massimo M et al. Brain 2023; 146 (3):1175-1185 Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection.
实验应用 : IHC-Fr
Wu CT et al. Cell 2023; 186 (1):112-130.e20 SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming.
实验应用 : IHC-Fr
Normandin E et al. Nat Commun 2023; 14 (1):574 High-depth sequencing characterization of viral dynamics across tissues in fatal COVID-19 reveals compartmentalized infection.
Fraternale A et al. FASEB J 2023; 37 (2):e22741 Targeting SARS-CoV-2 by synthetic dual-acting thiol compounds that inhibit Spike/ACE2 interaction and viral protein production.
Zhou Y et al. Nat Biotechnol 2023; 41 (1):128-139 A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.
实验应用 : ICC/IF
Giannakopoulos S et al. PLoS Pathog 2023; 19 (5):e1011409 In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury.
实验应用 : ICC/IF
Porter LM et al. Heliyon 2023; 9 (3):e14383 Cigarette smoke preferentially induces full length ACE2 expression in differentiated primary human airway cultures but does not alter the efficiency of cellular SARS-CoV-2 infection.
实验应用 : ICC/IF
Zanon M et al. World J Gastroenterol 2023; 29 (1):200-220 Liver pathology in COVID-19 related death and leading role of autopsy in the pandemic.
Roessler J et al. Biomedicines 2023; 11 (11) SARS-CoV-2 and Epstein-Barr Virus-like Particles Associate and Fuse with Extracellular Vesicles in Virus Neutralization Tests.
Hagelauer E et al. Viruses 2023; 15 (12) Tetherin Restricts SARS-CoV-2 despite the Presence of Multiple Viral Antagonists.
Stewart H et al. EMBO Rep 2023; 24 (12):e57224 Tetherin antagonism by SARS-CoV-2 ORF3a and spike protein enhances virus release.
Styles CT et al. EMBO Mol Med 2023; 15 (12):e17932 Propylene glycol inactivates respiratory viruses and prevents airborne transmission.
Angioni R et al. Cell Rep Med 2023; 4 (11):101266 RAGE engagement by SARS-CoV-2 enables monocyte infection and underlies COVID-19 severity.
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Giannakopoulos S et al. bioRxiv 2022; In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury.
Rinschen MM et al. Sci Signal 2022; 15 (762):eabo7940 VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney.
T Tanikawa et al. Molecules 2022; 27 (17):5405 Degradative Effect of Nattokinase on Spike Protein of SARS-CoV-2
实验应用 : IHC-P
Prahl M et al. Nat Commun 2022; 13 (1):4422 Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy.
实验应用 : WB
Tsuji S et al. Nat Aging 2022; 2 (2):115-124 SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response.
Cappelletto A et al. Front Cardiovasc Med 2022; 9:1013262 SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet procoagulant activity.
实验应用 : WB
Mu?oz-Al?a M? et al. bioRxiv 2022; Surface-modified measles vaccines encoding oligomeric, fusion-stabilized SARS-CoV-2 spike glycoproteins bypass measles seropositivity, boosting neutralizing antibody responses to omicron and historical variants.
实验应用 : WB
Reyes S et al. Sens Diagn 2022; 1 (6):1198-1208 Metal organic framework encapsulated tamavidin-Gluc reporter: application in COVID-19 spike antigen bioluminescent immunoassay.
Biering SB et al. Nat Commun 2022; 13 (1):7630 SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling.
实验应用 : ICC/IF
Meyer Zu Natrup C et al. J Clin Invest 2022; 132 (24) Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capacity.
实验应用 : ICC/IF
Peng R et al. EMBO Rep 2022; 23 (12):e55839 Human ZBP1 induces cell death-independent inflammatory signaling via RIPK3 and RIPK1.
实验应用 : WB
Petros BA et al. Med (N Y) 2022; Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework.
Gupta RK et al. EMBO J 2022; 41 (22):e111653 Cyclin D3 restricts SARS-CoV-2 envelope incorporation into virions and interferes with viral?spread.
实验应用 : WB
Prout A et al. Vaccine 2022; 40 (37):5529-5536 Functional profiling of Covid 19 vaccine candidate by flow virometry.
实验应用 : FACS
Takeda R et al. Sci Rep 2022; 12 (1):14050 Antiviral effect of cetylpyridinium chloride in mouthwash on SARS-CoV-2.
实验应用 : WB
Su P et al. Mol Brain 2022; 15 (1):71 Development of a novel peptide to prevent entry of SARS-CoV-2 into lung and olfactory bulb cells of hACE2 expressing mice.
实验应用 : WB, IP
Narayan R et al. J Hosp Infect 2022; 129:17-21 Efficient elimination of airborne pathogens: a study on?aerosolized Mycobacterium tuberculosis and SARS-CoV-2 using ZeBox technology.
实验应用 : ICC/IF
Mei S et al. Front Immunol 2022; 13:911164 Immunogenicity of a vaccinia virus-based severe acute respiratory syndrome coronavirus 2 vaccine candidate.
实验应用 : WB
Macedo S et al. Eur Thyroid J 2022; 11 (4) Detection of SARS-CoV-2 infection in thyroid follicular cells from a COVID-19 autopsy series.
实验应用 : IHC-P
Gao SY et al. Front Immunol 2022; 13:1038562 Nanocell COVID-19 vaccine triggers a novel immune response pathway producing high-affinity antibodies which neutralize all variants of concern.
Chen YT et al. Front Immunol 2022; 13:1080897 Methotrexate inhibition of SARS-CoV-2 entry, infection and inflammation revealed by bioinformatics approach and a hamster model.
Ogura H et al. Nat Commun 2022; 13 (1):7063 Dysfunctional Sars-CoV-2-M protein-specific cytotoxic T lymphocytes in patients recovering from severe COVID-19.
Kimura I et al. iScience 2022; 25 (12):105720 The SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variant.
Kim K et al. Front Immunol 2022; 13:1020165 Translation suppression underlies the restrained COVID-19 mRNA vaccine response in the high-risk immunocompromised group.
Lista MJ et al. J Virol 2022; 96 (23):e0125022 The P681H Mutation in the Spike Glycoprotein of the Alpha Variant of SARS-CoV-2 Escapes IFITM Restriction and Is Necessary for Type I Interferon Resistance.
Nasser H et al. STAR Protoc 2022; 3 (4):101773 Monitoring fusion kinetics of viral and target cell membranes in living cells using a SARS-CoV-2 spike-protein-mediated membrane fusion assay.
Lu Y et al. Mol Biol Cell 2022; 33 (14):ar147 SARS-CoV-2 down-regulates ACE2 through lysosomal degradation.
Tan TS et al. J Virol 2022; 96 (20):e0116222 Dissecting Naturally Arising Amino Acid Substitutions at Position L452 of SARS-CoV-2 Spike.
Kiyan Y et al. Sci Rep 2022; 12 (1):16878 Calcium dobesilate reduces SARS-CoV-2 entry into endothelial cells by inhibiting virus binding to heparan sulfate.
Weil T et al. JACS Au 2022; 2 (9):2187-2202 Advanced Molecular Tweezers with Lipid Anchors against SARS-CoV-2 and Other Respiratory Viruses.
Kumar CS et al. ACS Infect Dis 2022; 8 (10):2119-2132 Virus-Like Particles of SARS-CoV-2 as Virus Surrogates: Morphology, Immunogenicity, and Internalization in Neuronal Cells.
Vanhulle E et al. Front Cell Infect Microbiol 2022; 12:989534 Carbohydrate-binding protein from stinging nettle as fusion inhibitor for SARS-CoV-2 variants of concern.
Aicher SM et al. J Virol 2022; 96 (14):e0060822 Species-Specific Molecular Barriers to SARS-CoV-2 Replication in Bat Cells.
Shimizu K et al. Cancer Sci 2022; 113 (8):2536-2547 A single immunization with cellular vaccine confers dual protection against SARS-CoV-2 and cancer.
实验应用 : ELISA
Bullock HA et al. Front Med (Lausanne) 2022; 9:1099408 Probable vertical transmission of Alpha variant of concern (B.1.1.7) with evidence of SARS-CoV-2 infection in the syncytiotrophoblast, a case report.
实验应用 : IHC-P
Kong W et al. mBio 2022; 13 (6):e0230822 Neuropilin-1 Mediates SARS-CoV-2 Infection of Astrocytes in Brain Organoids, Inducing Inflammation Leading to Dysfunction and Death of Neurons.
实验应用 : ICC/IF, IHC-Fr
Yaron TM et al. Sci Signal 2022; 15 (757):eabm0808 Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.
实验应用 : WB
Song J et al. PLoS Biol 2022; 20 (10):e3001805 LRRC15 inhibits SARS-CoV-2 cellular entry in trans.
实验应用 : ICC/IF
Vanslambrouck JM et al. Nat Commun 2022; 13 (1):5943 Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids.
实验应用 : IHC-P
John SP et al. Cell Rep 2022; 41 (1):111441 Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection.
实验应用 : ICC/IF
Agostinis C et al. Front Immunol 2022; 13:957224 SARS-CoV-2 modulates virus receptor expression in placenta and can induce trophoblast fusion, inflammation and endothelial permeability.
实验应用 : ICC/IF
Drewry DH et al. J Med Chem 2022; 65 (19):12860-12882 Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses.
实验应用 : ICC/IF
Wee LE et al. IDCases 2022; 30:e01611 Detection of viable SARS-CoV-2 in deep respiratory specimens despite negative nasopharyngeal SARS-CoV-2 RT-PCR: Occult COVID-19 as an unsuspected cause of pulmonary infiltrates in immunocompromised patients.
实验应用 : IHC-P
Gourdelier M et al. Sci Rep 2022; 12 (1):14651 Optimized production and fluorescent labeling of SARS-CoV-2 virus-like particles.
实验应用 : WB
Jin JC et al. Pediatr Res 2022; SARS CoV-2 detected in neonatal stool remote from maternal COVID-19 during pregnancy.
实验应用 : ELISA
Hawman DW et al. EBioMedicine 2022; 83:104196 Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in na?ve hamsters compared to ancestral vaccine.
实验应用 : ELISA
Silva-Aguiar RP et al. Biochim Biophys Acta Mol Basis Dis 2022; 1868 (12):166496 SARS-CoV-2 spike protein inhibits megalin-mediated albumin endocytosis in proximal tubule epithelial cells.
实验应用 : ICC/IF, FACS
Tien CF et al. iScience 2022; 25 (8):104709 Glycosylation and S-palmitoylation regulate SARS-CoV-2 spike protein intracellular trafficking.
实验应用 : WB, ICC/IF
Baumeier C et al. Int J Mol Sci 2022; 23 (13) Intramyocardial Inflammation after COVID-19 Vaccination: An Endomyocardial Biopsy-Proven Case Series.
实验应用 : IHC-P
Park H et al. Adv Sci (Weinh) 2022; 9 (24):e2105320 TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike.
实验应用 : ICC/IF
Sefik E et al. Nature 2022; 606 (7914):585-593 Inflammasome activation in infected macrophages drives COVID-19 pathology.
实验应用 : ICC/IF
Yamamoto Y et al. Int J Mol Sci 2022; 24 (1) Direct Inhibition of SARS-CoV-2 Spike Protein by Peracetic Acid.
Yamamoto Y et al. Int J Mol Sci 2022; 23 (24) SARS-CoV-2 Spike Protein Mutation at Cysteine-488 Impairs Its Golgi Localization and Intracellular S1/S2 Processing.
Yeh CT et al. Biomedicines 2022; 10 (11) Immunoglobulin Y Specific for SARS-CoV-2 Spike Protein Subunits Effectively Neutralizes SARS-CoV-2 Infectivity and Ameliorates Disease Manifestations In Vivo.
Chan JF et al. Cell Rep Med 2022; 3 (10):100774 A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in?vivo.
Gellenoncourt S et al. J Virol 2022; 96 (19):e0130122 The Spike-Stabilizing D614G Mutation Interacts with S1/S2 Cleavage Site Mutations To Promote the Infectious Potential of SARS-CoV-2 Variants.
Wong YP et al. Int J Environ Res Public Health 2022; 19 (15) SARS-CoV-2 Infection in Pregnancy: Placental Histomorphological Patterns, Disease Severity and Perinatal Outcomes.
Sim JR et al. Cell Rep 2022; 40 (3):111117 Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition.
Jungwirth J et al. Int J Mol Sci 2022; 23 (13) D,L-Lysine-Acetylsalicylate + Glycine (LASAG) Reduces SARS-CoV-2 Replication and Shows an Additive Effect with Remdesivir.
Wettstein L et al. Commun Biol 2022; 5 (1):681 Peptidomimetic inhibitors of TMPRSS2 block SARS-CoV-2 infection in cell culture.
Willett BJ et al. Nat Microbiol 2022; 7 (8):1161-1179 SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway.
Mitsunaga M et al. Commun Biol 2022; 5 (1):647 Antimicrobial strategy for targeted elimination of different microbes, including bacterial, fungal and viral pathogens.
Escalera A et al. STAR Protoc 2022; 3 (3):101502 Protocol to isolate and assess spike protein cleavage in SARS-CoV-2 variants obtained from clinical COVID-19 samples.
Zhou Y et al. Res Sq 2022; A comprehensive SARS-CoV-2-human protein-protein interactome network identifies pathobiology and host-targeting therapies for COVID-19.
Kawano H et al. Intern Med 2022; 61 (15):2319-2325 Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination.
R?mi Plan?s et al. Mol Cell 2022; Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells.
实验应用 : IHC-P
Yuchao Chen et al. Sci Adv 2022; 8 (21):eabn3481 Quantitative and ultrasensitive in situ immunoassay technology for SARS-CoV-2 detection in saliva.
Amy R Rappaport et al. Nat Commun 2022; 13 (1):3289 Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection.
实验应用 : WB
Daichi Fujimoto et al. Med Mol Morphol 2022; Sputum characteristics of patients with severe COVID-19: report of two cases with immunocytochemical detection of SARS-CoV-2 spike protein.
Shilei Zhang et al. Cell Mol Immunol 2022; SARS-CoV-2 virus NSP14 Impairs NRF2/HMOX1 activation by targeting Sirtuin 1.
实验应用 : WB
Weijie Zeng et al. Front Cell Infect Microbiol 2022; 12:911313 Evidence of Infection of Human Embryonic Stem Cells by SARS-CoV-2.
实验应用 : WB
Ceri Alan Fielding et al. Elife 2022; 11 SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies.
实验应用 : FACS
Liu Cao et al. Sci Transl Med 2022;:eabm7621 The adenosine analog prodrug ATV006 is orally bioavailable and has preclinical efficacy against parental SARS-CoV-2 and variants.
实验应用 : IHC-P
Georg Jocher et al. EMBO Rep 2022; 23 (6):e54305 ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion.
Marica Grossegesse et al. J Proteome Res 2022; 21 (2):459-469 Deep Time Course Proteomics of SARS-CoV- and SARS-CoV-2-Infected Human Lung Epithelial Cells (Calu-3) Reveals Strong Induction of Interferon-Stimulated Gene Expression by SARS-CoV-2 in Contrast to SARS-CoV.
实验应用 : WB
Kah-Whye Peng et al. Vaccine 2022; 40 (15):2342-2351 Boosting of SARS-CoV-2 immunity in nonhuman primates using an oral rhabdoviral vaccine.
实验应用 : WB
Ravindra Gupta et al. Res Sq 2022; SARS-CoV-2 Omicron spike mediated immune escape and tropism shift.
实验应用 : WB, ICC/IF
Pehu?n Pereyra Gerber et al. PLoS Pathog 2022; 18 (2):e1010265 A protease-activatable luminescent biosensor and reporter cell line for authentic SARS-CoV-2 infection.
实验应用 : ICC/IF, FACS
Hang Yang et al. Virol Sin 2022; Cytoplasmic domain and enzymatic activity of ACE2 are not required for PI4KB dependent endocytosis entry of SARS-CoV-2 into host cells.
实验应用 : WB
Andreia L Pinto et al. Nat Commun 2022; 13 (1):1609 Ultrastructural insight into SARS-CoV-2 entry and budding in human airway epithelium.
Ningfei Ji et al. Emerg Microbes Infect 2022; 11 (1):1115-1125 SARS-CoV-2 in the pancreas and the impaired islet function in COVID-19 patients.
实验应用 : IHC-P
Chan Maung Nyein et al. J Hepatol 2022; Severe de novo liver injury after Moderna vaccination - not always autoimmune hepatitis.
实验应用 : IHC-P
Hiroki Hayashi et al. Curr Res Transl Med 2022; 70 (4):103348 Preclinical study of a DNA vaccine targeting SARS-CoV-2.
实验应用 : ELISA
Daichi Yamasoba et al. Cell 2022; Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike.
实验应用 : WB
Irina Panina et al. Int J Mol Sci 2022; 23 (9) Molecular Dynamics of DHHC20 Acyltransferase Suggests Principles of Lipid and Protein Substrate Selectivity.
实验应用 : WB
Alice Mac Kain et al. Nat Commun 2022; 13 (1):2442 Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen.
实验应用 : WB
Michael S Nirenberg et al. J Cutan Pathol 2022; Histopathology of persistent long COVID toe: A case report.
E Welsh et al. J Eur Acad Dermatol Venereol 2022; Negative SARS-CoV-2 antibodies in patients with positive immunohistochemistry for spike protein in pityriasis rosea-like eruptions.
Katharina R?ltgen et al. Cell 2022; 185 (6):1025-1040.e14 Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination.
实验应用 : IHC-P
Marco A D?az-Salinas et al. Elife 2022; 11 Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike.
实验应用 : WB, FACS, ELISA
Andres Santos et al. Mod Pathol 2022; Absence of SARS-CoV-2 Spike glycoprotein expression in placentas from individuals after mRNA SARS-CoV-2 vaccination.
实验应用 : IHC-P
Bo Meng et al. Nature 2022; Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity.
实验应用 : ICC/IF
Shahzaib Ahamad et al. Front Genet 2022; 13:866474 Anti-Fungal Drug Anidulafungin Inhibits SARS-CoV-2 Spike-Induced Syncytia Formation by Targeting ACE2-Spike Protein Interaction.
Yi-Chung Chang et al. EMBO Mol Med 2022; 14 (4):e15298 A siRNA targets and inhibits a broad range of SARS-CoV-2 infections including Delta variant.
实验应用 : IHC-P
Veronica Bordoni et al. iScience 2022; 25 (2):103854 The interplay between SARS-CoV-2 infected airway epithelium and immune cells modulates regulatory/inflammatory signals.
实验应用 : ICC/IF
Valeria Garcia-Flores et al. Nat Commun 2022; 13 (1):320 Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2.
实验应用 : IHC-P
Wenrui Guo et al. Life Sci Alliance 2022; 5 (4) Topical TMPRSS2 inhibition prevents SARS-CoV-2 infection in differentiated human airway cultures.
实验应用 : ICC/IF
Junyuan Cao et al. Viruses 2022; 14 (2) Screening of Botanical Drugs against SARS-CoV-2 Entry Reveals Novel Therapeutic Agents to Treat COVID-19.
实验应用 : WB
Silvia C Trevelin et al. Front Immunol 2022; 13:838328 Disrupted Peyer's Patch Microanatomy in COVID-19 Including Germinal Centre Atrophy Independent of Local Virus.
实验应用 : IHC-P
Yasuo Ariumi et al. J Virol 2022; 96 (6):e0000222 Host Cellular RNA Helicases Regulate SARS-CoV-2 Infection.
实验应用 : WB
Nicola Wanner et al. Nat Metab 2022; 4 (3):310-319 Molecular consequences of SARS-CoV-2 liver tropism.
实验应用 : IHC-P
Anna Riccio et al. Cell Mol Life Sci 2022; 79 (5):227 Impairment of SARS-CoV-2 spike glycoprotein maturation and fusion activity by nitazoxanide: an effect independent of spike variants emergence.
Baris Boyraz et al. Hum Pathol 2022; Placental pathology from COVID-19-recovered (nonacute) patients.
实验应用 : IHC-P
Singh RD et al. Biochim Biophys Acta Mol Basis Dis 2022; 1868 (3):166322 The spike protein of SARS-CoV-2 induces heme oxygenase-1: Pathophysiologic implications.
实验应用 : WB
Dorman LC et al. bioRxiv 2022; A type I interferon response defines a conserved microglial state required for effective neuronal phagocytosis.
实验应用 : ICC/IF
Ramadan AA et al. Viruses 2022; 14 (3) Identification of SARS-CoV-2 Spike Palmitoylation Inhibitors That Results in Release of Attenuated Virus with Reduced Infectivity.
实验应用 : FACS
Magalh?es AC et al. Pathogens 2022; 11 (3) InfectionCMA: A Cell MicroArray Approach for Efficient Biomarker Screening in In Vitro Infection Assays.
实验应用 : ICC/IF
Gehlhausen JR et al. Proc Natl Acad Sci U S A 2022; 119 (9) Lack of association between pandemic chilblains and SARS-CoV-2 infection.
实验应用 : IHC-P
Neuberger M et al. Infection 2022; Duodenal tropism of SARS-CoV-2 and clinical findings in critically ill COVID-19 patients.
实验应用 : IHC-P
Matsuoka K et al. J Biol Chem 2022;:101724 SARS-CoV-2 accessory protein ORF8 is secreted extracellularly as a glycoprotein homodimer.
实验应用 : WB
Suzuki R et al. Nature 2022; (Epub) Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant.
实验应用 : WB, ICC/IF
Kung YA et al. mBio 2022;:e0271721 Acyl-Coenzyme A Synthetase Long-Chain Family Member 4 Is Involved in Viral Replication Organelle Formation and Facilitates Virus Replication via Ferroptosis.
实验应用 : ICC/IF
Kim Y et al. Cell Mol Immunol 2022; (Epub) MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination.
Wan L et al. Nat Metab 2022; (Epub) GP73 is a glucogenic hormone contributing to SARS-CoV-2-induced hyperglycemia.
实验应用 : ICC/IF
Fenizia C et al. Microbiol Spectr 2022;:e0150421 Cyclosporine A Inhibits Viral Infection and Release as Well as Cytokine Production in Lung Cells by Three SARS-CoV-2 Variants.
Tada T et al. Cell Rep 2022; 38 (2):110237 High-titer neutralization of Mu and C.1.2 SARS-CoV-2 variants by vaccine-elicited antibodies of previously infected individuals.
实验应用 : WB
Hassler L et al. Clin J Am Soc Nephrol 2021; 16 (11):1755-1765 Evidence For and Against Direct Kidney Infection by SARS-CoV-2 in Patients with COVID-19.
Wen-Fang Tang et al. Biomed J 2021; 44 (3):293-303 Perilla (Perilla frutescens) leaf extract inhibits SARS-CoV-2 via direct virus inactivation.
实验应用 : WB
Benjamin C Jennings et al. FEBS Lett 2021; 595 (13):1758-1767 A weak COPI binding motif in the cytoplasmic tail of SARS-CoV-2 spike glycoprotein is necessary for its cleavage, glycosylation, and localization.
实验应用 : WB, ICC/IF
Patthara Kongsuphol et al. Commun Med (Lond) 2021; 1:46 A rapid simple point-of-care assay for the detection of SARS-CoV-2 neutralizing antibodies.
Cheng Wang et al. Cell Stem Cell 2021; 28 (2):331-342.e5 ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response.
实验应用 : ICC/IF
H Stewart et al. bioRxiv 2021; SARS-CoV-2 spike downregulates tetherin to enhance viral spread.
实验应用 : ICC/IF
Xin Yin et al. Cell Rep 2021; 34 (2):108628 MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells.
实验应用 : WB
Luke Lee et al. Res Sq 2021; Quantitative and Ultrasensitive In-situ Immunoassay Technology for SARS-CoV-2 Detection in Saliva.
Armin Bayati et al. J Biol Chem 2021;:100306 SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis.
实验应用 : WB, ICC/IF
Maria Casagrande et al. JAMA Ophthalmol 2021; 139 (4):383-388 Presence of SARS-CoV-2 RNA in the Cornea of Viremic Patients With COVID-19.
实验应用 : IHC-P
Jerzy Osipiuk et al. Nat Commun 2021; 12 (1):743 Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors.
实验应用 : ICC/IF
Nanda Kishore Routhu et al. Immunity 2021; A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs.
实验应用 : WB
Taha Azad et al. Mol Ther 2021; Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2?S for viral entry.
实验应用 : Neutralizing/Inhibition
Erica D Dawson et al. J Virol Methods 2021;:114111 Multiplexed, microscale, microarray-based serological assay for antibodies against all human-relevant coronaviruses.
实验应用 : ELISA
Kentaro Uemura et al. Sci Rep 2021; 11 (1):5376 MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2.
实验应用 : ICC/IF
Shahanshah Khan et al. bioRxiv 2021; SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway.
实验应用 : FACS
Ruklanthi de Alwis et al. Mol Ther 2021; 29 (6):1970-1983 A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice.
实验应用 : WB
Maria Casagrande et al. Br J Ophthalmol 2021; Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19.
实验应用 : IHC-P
Jamie M Walker et al. J Neuropathol Exp Neurol 2021; 80 (6):628-631 COVID-19 Patients With CNS Complications and Neuropathologic Features of Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalopathy.
Stefanie Deinhardt-Emmer et al. J Virol 2021; SARS-CoV-2 causes severe epithelial inflammation and barrier dysfunction.
实验应用 : ICC/IF
Manuel Hayn et al. Cell Rep 2021; 35 (7):109126 Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities.
实验应用 : WB
Yun Teng et al. Mol Ther 2021; Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12.
实验应用 : WB
Toshiki Ebisudani et al. Cell Rep 2021;:109218 Direct derivation of human alveolospheres for SARS-CoV-2 infection modeling and drug screening.
实验应用 : ICC/IF
Akinari Tsukada et al. Intern Med 2021; 60 (14):2297-2300 A Kidney Transplant Patient Who Died of COVID-19-associated Severe Acute Respiratory Distress Syndrome.
实验应用 : IHC-P
Rianna Vandergaast et al. mSphere 2021; 6 (3):e0017021 IMMUNO-COV v2.0: Development and Validation of a High-Throughput Clinical Assay for Measuring SARS-CoV-2-Neutralizing Antibody Titers.
实验应用 : WB
S?bastien Lyonnais et al. Sci Rep 2021; 11 (1):11885 Atomic force microscopy analysis of native infectious and inactivated SARS-CoV-2 virions.
实验应用 : WB
Carolina da S G Pedrosa et al. Stem Cell Res 2021; 54:102436 Non-permissive SARS-CoV-2 infection in human neurospheres.
实验应用 : WB
Jakob Trimpert et al. Cell Rep 2021;:109493 Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding.
实验应用 : WB
Dickson W L Wong et al. Cells 2021; 10 (8) Multisystemic Cellular Tropism of SARS-CoV-2 in Autopsies of COVID-19 Patients.
实验应用 : IHC-P
Caterina Prelli Bozzo et al. Nat Commun 2021; 12 (1):4584 IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro.
实验应用 : WB
Drucilla J Roberts et al. Am J Obstet Gynecol 2021; A standardized definition of placental infection by SARS-CoV-2, a consensus statement from the National?Institutes of Health/Eunice Kennedy Shriver National?Institute of Child Health and Human Development?SARS-CoV-2 Placental Infection Workshop.
Elaine C Chen et al. Cell Rep 2021; 36 (8):109604 Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals.
Abhijith Biji et al. EBioMedicine 2021; 70:103525 Identification of COVID-19 prognostic markers and therapeutic targets through meta-analysis and validation of Omics data from nasopharyngeal samples.
实验应用 : WB
Xiangchuan He et al. Emerg Microbes Infect 2021; 10 (1):1555-1573 A human cell-based SARS-CoV-2 vaccine elicits potent neutralizing antibody responses and protects mice from SARS-CoV-2 challenge.
实验应用 : ICC/IF
Fabian Zech et al. Nat Commun 2021; 12 (1):6855 Spike residue 403 affects binding of coronavirus spikes to human ACE2.
实验应用 : WB
Shahanshah Khan et al. Elife 2021; 10 SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway.
实验应用 : WB, FACS
Sung-Chan Wei et al. Front Immunol 2021; 12:771011 An Integrated Platform for Serological Detection and Vaccination of COVID-19.
实验应用 : WB, ICC/IF, ELISA
Michihito Sasaki et al. mBio 2021; 12 (4):e0141521 SARS-CoV-2 Bearing a Mutation at the S1/S2 Cleavage Site Exhibits Attenuated Virulence and Confers Protective Immunity.
实验应用 : IHC-P
Rakesh Kulkarni et al. PLoS One 2021; 16 (9):e0257191 Vaccinia virus-based vaccines confer protective immunity against SARS-CoV-2 virus in Syrian hamsters.
实验应用 : WB
Xiaoquan Li et al. PLoS Pathog 2021; 17 (9):e1009898 Ethacridine inhibits SARS-CoV-2 by inactivating viral particles.
实验应用 : ICC/IF
Carmen Mirabelli et al. Proc Natl Acad Sci U S A 2021; 118 (36) Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19.
实验应用 : ICC/IF
Tsuguhisa Nakayama et al. Cell Rep Med 2021; 2 (10):100421 Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers.
实验应用 : IHC-P
Shu Liu et al. Nat Commun 2021; 12 (1):5739 Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions.
实验应用 : WB
Riccardo De Santis et al. J Photochem Photobiol 2021; 8:100082 Rapid inactivation of SARS-CoV-2 with LED irradiation of visible spectrum wavelengths.
实验应用 : WB
Kasopefoluwa Y Oguntuyo et al. mBio 2021; 12 (1) Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera.
实验应用 : WB
Hsu-Yu Chen et al. J Virol 2021; 95 (22):e0096621 Cytoplasmic Tail Truncation of SARS-CoV-2 Spike Protein Enhances Titer of Pseudotyped Vectors but Masks the Effect of the D614G Mutation.
实验应用 : WB
Barbara Storti et al. Comput Struct Biotechnol J 2021; 19:6140-6156 A spatial multi-scale fluorescence microscopy toolbox discloses entry checkpoints of SARS-CoV-2 variants in Vero E6 cells.
实验应用 : WB
Marta De Angelis et al. Biomedicines 2021; 9 (11) Protective Role of Combined Polyphenols and Micronutrients against Influenza A Virus and SARS-CoV-2 Infection In Vitro.
实验应用 : WB
Biering SB et al. bioRxiv 2021; SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling.
Zhao L et al. MedComm (2020) 2021; SARS-CoV-2 spike protein harnesses SNX27-mediated endocytic recycling pathway.
实验应用 : FACS
Song J et al. bioRxiv 2021; LRRC15 is an inhibitory receptor blocking SARS-CoV-2 spike-mediated entry in trans.
Yokoi S. et al. Eur J Dermatol. 2021; 31 (4):568-570 COVID-19-associated livedo and purpura: clinical and histopathological findings.
实验应用 : IHC-P
Kongsuphol P. et al. Communications Medicine 2021; (Epub) A rapid simple point-of-care assay for the detection of SARS-CoV-2 neutralizing antibodies.
Zhang Z et al. Cell Death Differ 2021; 28 (9):2765-2777 SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
实验应用 : WB
Rosner-Tenerowicz A et al. BMC Pregnancy Childbirth 2021; 21 (1):760 Placental pathology in a pregnant woman with severe COVID-19 and successful ECMO treatment: a case report.
实验应用 : IHC-P
Al-Beltagi S et al. Virulence 2021; 12 (1):2946-2956 Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin.
实验应用 : ICC/IF
Ohtsuka J et al. iScience 2021; 24 (12):103379 Non-propagative human parainfluenza virus type 2 nasal vaccine robustly protects the upper and lower airways against SARS-CoV-2.
实验应用 : WB
Saito A et al. Nature 2021; Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation.
实验应用 : WB
Kim M et al. Biomedicines 2021; 9 (11) In Vitro Replication Inhibitory Activity of Xanthorrhizol against Severe Acute Respiratory Syndrome Coronavirus 2.
Zhong C et al. NPJ Vaccines 2021; 6 (1):139 Mucosal vaccination induces protection against SARS-CoV-2 in the absence of detectable neutralizing antibodies.
实验应用 : WB
Xiao Y et al. Cell 2021; 184 (25):6037-6051.e14 A defective viral genome strategy elicits broad protective immunity against respiratory viruses.
实验应用 : IHC-P
Zhao L. et al. MedComm 2021; (Epub) SARS-CoV-2 spike protein harnesses SNX27-mediated endocytic recycling pathway.
实验应用 : ICC/IF
Shue B et al. J Virol 2021; 95 (24):e0059621 Genome-Wide CRISPR Screen Identifies RACK1 as a Critical Host Factor for Flavivirus Replication.
实验应用 : WB
Johnson JE et al. Am J Pathol 2021; (Epub) Coronavirus Disease 2019 (COVID-19) Coronary Vascular Thrombosis: Correlation with Neutrophil but Not Endothelial Activation.
实验应用 : IHC-P
Carter-Timofte ME et al. ACS Infect Dis 2021; 7 (11):3034-3051 Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern.
实验应用 : FACS
Kudose S et al. J Am Soc Nephrol 2021; 32 (11):2958-2969 Longitudinal Outcomes of COVID-19-Associated Collapsing Glomerulopathy and Other Podocytopathies.
实验应用 : IHC-P
Ren H et al. Biol Direct 2021; 16 (1):20 Micronucleus production, activation of DNA damage response and cGAS-STING signaling in syncytia induced by SARS-CoV-2 infection.
实验应用 : WB
Tada T et al. iScience 2021; 24 (11):103341 Partial resistance of SARS-CoV-2 Delta variants to vaccine-elicited antibodies and convalescent sera.
实验应用 : WB
Kim DH et al. Sci Rep 2021; 11 (1):21462 Hemin as a novel candidate for treating COVID-19 via heme oxygenase-1 induction.
实验应用 : ICC/IF
Thyrsted J et al. iScience 2021; 24 (11):103300 Influenza A induces lactate formation to inhibit type I IFN in primary human airway epithelium.
实验应用 : WB
Seo JS et al. Viruses 2021; 13 (8) The Microvillar and Solitary Chemosensory Cells as the Novel Targets of Infection of SARS-CoV-2 in Syrian Golden Hamsters.
实验应用 : IHC-P
Gomes I et al. Lancet Reg Health Am 2021; 2:100046 SARS-CoV-2 infection of the central nervous system in a 14-month-old child: A case report of a complete autopsy.
实验应用 : IHC-P
Uemura K et al. iScience 2021; 24 (10):103120 5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2.
实验应用 : ICC/IF
Navaratnarajah CK et al. J Virol 2021;:JVI0136821 Highly efficient SARS-CoV-2 infection of human cardiomyocytes: spike protein-mediated cell fusion and its inhibition.
实验应用 : WB, ICC/IF, FACS
Cheng YW et al. mBio 2021; 12 (4):e0058721 D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Virus Titer via Enhanced Furin-Mediated Spike Cleavage.
实验应用 : WB
Araujo-Silva CA et al. JAMA Ophthalmol 2021; 139 (9):1015-1021 Presumed SARS-CoV-2 Viral Particles in the Human Retina of Patients With COVID-19.
实验应用 : WB
Dal Ferro M et al. Clin Res Cardiol 2021; (Epub) SARS-CoV-2, myocardial injury and inflammation: insights from a large clinical and autopsy study.
实验应用 : IHC-P
Lam LKM et al. Am J Physiol Lung Cell Mol Physiol 2021; 321 (2):L485-L489 Erythrocytes identify complement activation in patients with COVID-19.
Sasaki M. et al. PLoS Pathog. 2021; 17 (1):e1009233 SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells.
实验应用 : ICC/IF
Tada T et al. mBio 2021; 12 (3):e0069621 Convalescent-Phase Sera and Vaccine-Elicited Antibodies Largely Maintain Neutralizing Titer against Global SARS-CoV-2 Variant Spikes.
实验应用 : WB
Matsuura R et al. Viruses 2021; 13 (5) SARS-CoV-2 Disinfection of Air and Surface Contamination by TiO2 Photocatalyst-Mediated Damage to Viral Morphology, RNA, and Protein.
实验应用 : WB
Wu CT et al. Cell Metab 2021; 33 (8):1565-1576.e5 SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment.
Colson A et al. Am J Pathol 2021; 191 (9):1610-1623 Clinical and in?Vitro Evidence against Placenta Infection at Term by Severe Acute Respiratory Syndrome Coronavirus 2.
实验应用 : IHC-P
Masterson AN et al. Anal Chem 2021; 93 (25):8754-8763 Multiplexed and High-Throughput Label-Free Detection of RNA/Spike Protein/IgG/IgM Biomarkers of SARS-CoV-2 Infection Utilizing Nanoplasmonic Biosensors.
Yang AC et al. Nature 2021; 595 (7868):565-571 Dysregulation of brain and choroid plexus cell types in severe COVID-19.
实验应用 : IHC-P
Higuchi Y et al. Nat Commun 2021; 12 (1):3802 Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2.
实验应用 : IHC-P
Fenizia C et al. Cells 2021; 10 (6) SARS-CoV-2 Entry: At the Crossroads of CD147 and ACE2.
实验应用 : WB
Ciccosanti F et al. Antiviral Res 2021; 190:105064 Proteomic analysis identifies the RNA helicase DDX3X as a host target against SARS-CoV-2 infection.
实验应用 : WB, ICC/IF
P?rez A et al. Viruses 2021; 13 (4) IgA-Dominant Infection-Associated Glomerulonephritis Following SARS-CoV-2 Infection.
实验应用 : IHC-P
Braga L et al. Nature 2021; 594 (7861):88-93 Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia.
实验应用 : ICC/IF
Sui Y et al. JCI Insight 2021; 6 (10) Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques.
实验应用 : IHC-P
Kim YJ et al. Viruses 2021; 13 (4) The Impact on Infectivity and Neutralization Efficiency of SARS-CoV-2 Lineage B.1.351 Pseudovirus.
实验应用 : WB
Di Domenico M et al. Diagnostics (Basel) 2021; 11 (4) Detection of SARS-COV-2 Proteins Using an ELISA Test.
Harbour JC et al. J Immunol 2021; 206 (11):2596-2604 Cellular and Humoral Immune Responses in Mice Immunized with Vaccinia Virus Expressing the SARS-CoV-2 Spike Protein.
实验应用 : WB
Gutmann C et al. Nat Commun 2021; 12 (1):3406 SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care.
Kumar A et al. J Virol 2021; 95 (13):e0026621 SARS-CoV-2 Nonstructural Protein 1 Inhibits the Interferon Response by Causing Depletion of Key Host Signaling Factors.
Roden AC et al. Arch Pathol Lab Med 2021; 145 (7):785-796 Comparison of In Situ Hybridization, Immunohistochemistry, and Reverse Transcription-Droplet Digital Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Testing in Tissue.
实验应用 : IHC-P
Liu G et al. Nat Microbiol 2021; 6 (4):467-478 ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity.
实验应用 : WB
Huang N et al. Nat Med 2021; 27 (5):892-903 SARS-CoV-2 infection of the oral cavity and saliva.
实验应用 : IHC-P
Dicken SJ et al. bioRxiv 2021; Characterisation of B.1.1.7 and Pangolin coronavirus spike provides insights on the evolutionary trajectory of SARS-CoV-2.
实验应用 : WB
Yamada T. et al. Nat Immunol 2021; (Epub) RIG-I triggers a signaling-abortive anti-SARS-CoV-2 defense in human lung cells.
实验应用 : ICC/IF
Winstone H et al. J Virol 2021; 95 (9) The Polybasic Cleavage Site in SARS-CoV-2 Spike Modulates Viral Sensitivity to Type I Interferon and IFITM2.
实验应用 : WB
Monte-Serrano J et al. Dermatol Ther 2021;:e14897 Granuloma annulare triggered by SARS-CoV-2 infection: Immunohistochemical staining.
实验应用 : IHC-P
Azad T et al. Biosens Bioelectron 2021; 180:113122 SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition.
Yeung ML et al. Cell 2021; 184 (8):2212-2228.e12 Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system.
Sharma P et al. Clin Kidney J 2021; 14 (Suppl 1):i30-i39 Pathology of COVID-19-associated acute kidney injury.
实验应用 : IHC-P
Cheng Y.W. et al. bioRxiv 2021; (Epub) D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Viral Transmission via Enhanced Furin-mediated Spike Cleavage.
实验应用 : WB
Garc?a-Arriaza J et al. J Virol 2021; (Epub) COVID-19 vaccine candidates based on modified vaccinia virus Ankara expressing the SARS-CoV-2 spike induce robust T- and B-cell immune responses and full efficacy in mice.
实验应用 : WB
Jang Y et al. Sci Rep 2021; 11 (1):821 Antiviral activity of lambda-carrageenan against influenza viruses and severe acute respiratory syndrome coronavirus 2.
实验应用 : ICC/IF
Linehan L et al. Placenta 2021; 104:261-266 SARS-CoV-2 placentitis: An uncommon complication of maternal COVID-19.
实验应用 : IHC-P
Lu-Culligan A et al. medRxiv 2021; (Epub) SARS-CoV-2 infection in pregnancy is associated with robust inflammatory response at the maternal-fetal interface.
实验应用 : IHC-P
Zhou H et al. bioRxiv 2021; (Epub) B.1.526 SARS-CoV-2 variants identified in New York City are neutralized by vaccine-elicited and therapeutic monoclonal antibodies.
Lamers MM et al. Elife 2021; 10 Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation.
实验应用 : WB
Wang L et al. Theranostics 2021; 11 (2):649-664 Rapid design and development of CRISPR-Cas13a targeting SARS-CoV-2 spike protein.
实验应用 : WB, ICC/IF
Jang Y et al. Int J Mol Sci 2021; 22 (4)
实验应用 : ICC/IF
Di Teodoro G et al. Vet Microbiol 2021; 252:108933 SARS-CoV-2 replicates in respiratory ex vivo organ cultures of domestic ruminant species.
实验应用 : IHC-P
Welsh E et al. Br J Dermatol 2021; (Epub) SARS-CoV-2 Spike Protein Positivity in Pityriasis Rosea-like and Urticaria-like Rashes of COVID-19.
实验应用 : IHC-P
Rebendenne A et al. J Virol 2021; (Epub) SARS-CoV-2 triggers an MDA-5-dependent interferon response which is unable to control replication in lung epithelial cells.
实验应用 : WB
Ozono S et al. Nat Commun 2021; 12 (1):848 SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity.
实验应用 : WB
Tada T et al. bioRxiv 2021; (Epub) Neutralization of viruses with European, South African, and United States SARS-CoV-2 variant spike proteins by convalescent sera and BNT162b2 mRNA vaccine-elicited antibodies.
实验应用 : WB
Eric Song et al. J Exp Med 2021; 218 (3):e20202135 Neuroinvasion of SARS-CoV-2 in human and mouse brain.
实验应用 : IHC-P
Jana Kr?ger et al. Cell Mol Gastroenterol Hepatol 2020; Drug Inhibition of SARS-CoV-2 Replication in Human Pluripotent Stem Cell-Derived Intestinal Organoids.
实验应用 : ICC/IF
Mirko Cortese et al. Cell Host Microbe 2020; 28 (6):853-866.e5 Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies.
实验应用 : ICC/IF
Takuya Tada et al. Cell Rep 2020;:108528 An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2.
实验应用 : WB
Carmen Mirabelli et al. bioRxiv 2020; Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19.
实验应用 : ICC/IF
Alberto Priori et al. Front Public Health 2020; 8:575029 The Many Faces of Covid-19 at a Glance: A University Hospital Multidisciplinary Account From Milan, Italy.
实验应用 : IHC-P
Katsura H et al. Cell Stem Cell 2020; 27 (6):890-904.e8 Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.
Nchioua R et al. mBio 2020; 11 (5) SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans.
Cheng YW et al. Cell Rep 2020; 33 (2):108254 Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects.
Conzelmann C et al. J Extracell Vesicles 2020; 9 (1):1808281 Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection.
Song E et al. bioRxiv 2020; (Epub) Neuroinvasion of SARS-CoV-2 in human and mouse brain.
Ramani A et al. EMBO J 2020; 39 (20):e106230 SARS-CoV-2 targets neurons of 3D human brain organoids.
Conzelmann C et al. Antiviral Res 2020; 181:104882 An enzyme-based immunodetection assay to quantify SARS-CoV-2 infection.
Chiuppesi F et al. bioRxiv 2020; Development of a Synthetic Poxvirus-Based SARS-CoV-2 Vaccine.
Lokugamage KG et al. bioRxiv 2020; (Epub) SARS-CoV-2 is sensitive to type I interferon pretreatment.
Havranek KE et al. Viruses 2020; 12 (12) SARS-CoV-2 Spike Alterations Enhance Pseudoparticle Titers and Replication-Competent VSV-SARS-CoV-2 Virus.
实验应用 : WB
Bernard I et al. Viruses 2020; 13 (1) Endothelium Infection and Dysregulation by SARS-CoV-2: Evidence and Caveats in COVID-19.
实验应用 : ICC/IF
Vandergaast R et al. bioRxiv 2020; (Epub) Development and validation of IMMUNO-COV?: a high-throughput clinical assay for detecting antibodies that neutralize SARS-CoV-2.
实验应用 : WB
Gao C et al. bioRxiv 2020; (Epub) SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors.
实验应用 : WB
Heaton BE et al. bioRxiv 2020; (Epub) SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2.
实验应用 : ICC/IF
Oguntuyo KY et al. medRxiv 2020; (Epub) Quantifying absolute neutralization titers against SARS-CoV-2 by a standardized virus neutralization assay allows for cross-cohort comparisons of COVID-19 sera.
实验应用 : WB
Drayman N et al. bioRxiv 2020; (Epub) Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro.
实验应用 : IHC-P
Olagnier D et al. Nat Commun 2020; 11 (1):4938 SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate.
实验应用 : WB
Dalskov L et al. EMBO Rep 2020;:e51252 SARS-CoV-2 evades immune detection in alveolar macrophages.
实验应用 : WB
Pellegrini L et al. Cell Stem Cell 2020; 27 (6):951-961.e5 SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids.
实验应用 : IHC-P
Li X et al. bioRxiv 2020; (Epub) Ethacridine inhibits SARS-CoV-2 by inactivating viral particles in cellular models.
实验应用 : IHC-P
Chiuppesi F et al. Nat Commun 2020; 11 (1):6121 Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform.
实验应用 : FACS
Ng JH et al. Adv Chronic Kidney Dis 2020; 27 (5):365-376 Pathophysiology and Pathology of Acute Kidney Injury in Patients With COVID-19.
实验应用 : IHC-P
Swann H et al. Sci Rep 2020; 10 (1):21877 Minimal system for assembly of SARS-CoV-2 virus like particles.
实验应用 : EM
Kuo-Yen Huang et al. EMBO Mol Med 2020;:e12828 Humanized COVID-19 decoy antibody effectively blocks viral entry and prevents SARS-CoV-2 infection.
实验应用 : WB
Zhao CL et al. Hum Pathol 2020; (Epub) Pathological findings in the postmortem liver of COVID-19 patients.
实验应用 : IHC-P
Jacob E Valk et al. J Perinatol. 2020;:1-3 Detection of SARS-CoV-2 in placental but not fetal tissues in the second trimester.
实验应用 : IHC-P
Cristiane J Nunes-Santos et al. J Clin Immunol. 2020;:1-10 N-Glycan Modification in Covid-19 Pathophysiology: In vitro Structural Changes with Limited Functional Effects.
实验应用 : WB
Congwen Wei et al. Nat Metab. 2020; (Epub) HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry.
实验应用 : ICC/IF
Caroline B Plescia et al. J Biol Chem. 2020;:jbc.RA120.016148. SARS-CoV-2 viral budding and entry can be modeled using BSL-2 level virus-like particles.
实验应用 : WB, ICC/IF
Hattori SI et al. mBio 2020; 11 (4) GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection.
实验应用 : ICC/IF
Boix-Vilanova J et al. Int J Dermatol 2020; (Epub) Grover-like skin eruption: another cutaneous manifestation in a COVID-19 patient.
实验应用 : IHC-P
Ian Gallicano G et al. Gene Ther 2020; (Epub) Molecular targeting of vulnerable RNA sequences in SARS CoV-2: identifying clinical feasibility.
实验应用 : WB, ICC/IF
Rossana Bussani et al. EBioMedicine 2020;:103104 Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology.
Laura Varela Barca et al. Interact Cardiovasc Thorac Surg 2020; (Epub) An unexplained death after routine cardiac surgery: how long have we dealt with coronavirus disease 2019?
实验应用 : IHC-P
Carolina da S G Pedrosa et al. bioRxiv 2020;:2020.09.11.293951 Non-permissive SARS-CoV-2 infection of neural cells in the developing human brain and neurospheres.
实验应用 : WB, IHC-P
Kumari G Lokugamage et al. J Virol. 2020;:JVI.01410-20 Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV.
实验应用 : WB
Hongjie Xia et al. Cell Rep. 2020; 33 (1):108234 Evasion of Type I Interferon by SARS-CoV-2.
实验应用 : WB
Chiuppesi F et al. Res Sq 2020; Development of a Multi-Antigenic SARS-CoV-2 Vaccine Using a Synthetic Poxvirus Platform.
实验应用 : FACS
Andina D et al. Pediatr Dermatol 2020; Suspected COVID-19-related reticulated purpura of the soles in an infant.
实验应用 : IHC-P
Szabolcs M et al. Appl Immunohistochem Mol Morphol 2020; Identification of Immunohistochemical Reagents for In Situ Protein Expression Analysis of Coronavirus-associated Changes in Human Tissues.
实验应用 : IHC-P
Thomas Mandel Clausen et al. Cell 2020; S0092-8674 (20):31230-7 SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2.
实验应用 : FACS
Jakob Matschke et al. Lancet Neurol. 2020; S1474-4422 (20):30308-2 Neuropathology of patients with COVID-19 in Germany: a post-mortem case series.
实验应用 : IHC-P
Kellie J Goodlet et al. Transpl Infect Dis 2020;:e13480 COVID-19 in a Lung Transplant Recipient: Exploring the Diagnostic Role of Circulating Exosomes and the Clinical Impact of Advanced Immunosuppression.
实验应用 : WB
T Gambichler et al. J Eur Acad Dermatol Venereol. 2020; (Epub) SARS-CoV-2 spike protein is present in both endothelial and eccrine cells of a chilblain-like skin lesion.
实验应用 : IHC-P
Alain C Borczuk et al. Mod Pathol. 2020; (Epub) COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City.
实验应用 : IHC-P
Antonio Torrelo et al. Pediatr Dermatol. 2020;:10.1111/pde.14246. Erythema multiforme‐like lesions in children and COVID‐19.
实验应用 : IHC-P
Appelberg S et al. Emerg Microbes Infect 2020; 9 (1):1748-1760 Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells.
Mariano Carossino et al. Arch Virol 2020; 5:1-5 Detection of SARS-CoV-2 by RNAscope ® in situ hybridization and immunohistochemistry techniques.
实验应用 : IHC-P
Christine J Ko et al. J Cutan Pathol . 2020; (Epub) Perniosis during the COVID-19 pandemic: Negative Anti-SARS-CoV-2 Immunohistochemistry in Six Patients and Comparison to Perniosis Before the Emergence of SARS-CoV-2.
实验应用 : IHC-P
Benjamin T Bradley et al. Lancet 2020; S0140-6736 (20):31305-2 Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series.
实验应用 : IHC-P
Satoru Kudose et al. J Am Soc Nephrol 2020;:ASN.2020060802 Kidney Biopsy Findings in Patients with COVID-19.
实验应用 : IHC-P
Bianca Pulinx et al. Eur J Clin Microbiol Infect Dis 2020; 13:1-15 Vertical transmission of SARS-CoV-2 infection and preterm birth.
实验应用 : IHC-P
Laura Prieto-Pérez et al. Mod Pathol 2020; (Epub) Histiocytic Hyperplasia With Hemophagocytosis and Acute Alveolar Damage in COVID-19 Infection.
实验应用 : IHC-P
C Santonja et al. Br J Dermatol 2020; (Epub) COVID-19 Chilblain-Like Lesion: Immunohistochemical Demonstration of SARS-CoV-2 Spike Protein in Blood Vessel Endothelium and Sweat Gland Epithelium in a PCR-negative Patient.
实验应用 : IHC-P
I Colmenero et al. Br J Dermatol 2020; (Epub) SARS-CoV-2 Endothelial Infection Causes COVID-19 Chilblains: Histopathological, Immunohistochemical and Ultraestructural Study of 7 Paediatric Cases.
实验应用 : IHC-P
Clone Reference
Zhiqiang Zheng et al. 2020; (Epub) Monoclonal antibodies for the S2 subunit of spike of SARS-CoV cross-react with the newly-emerged SARS-CoV-2.
实验应用 : ICC/IF
Kuo-Ming Lip et al. J Virol . 2006; 80 (2):941-50 Monoclonal Antibodies Targeting the HR2 Domain and the Region Immediately Upstream of the HR2 of the S Protein Neutralize in Vitro Infection of Severe Acute Respiratory Syndrome Coronavirus.
实验应用 : WB
种属反应 : SARS Coronavirus
SDS
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